On Demand Grand Rounds: Improving the Outcomes of Antidepressant Pharmacotherapy for Older Adults

CZARINA SANTOS-BORJA, MD MEMORIAL LECTURE

This presentation was originally reviewed on May 3, 2023, and broadcast live online on May 3, 2023, from 12:00 PM – 1:00 PM ET. 

The views and opinions expressed by this presenter in this lecture are their own, and do not represent the views of Sheppard Pratt.

Depressive and anxiety disorders are the most prevalent treatable mental disorders in older adults. Recovery from these disorders can occur in almost all patients and makes a dramatic difference in their level of functioning and quality of life. The proportion of older Americans being treated with an antidepressant (19%) has more than sextupled over the past two decades. However, most older patients do not appear to benefit from their antidepressant treatment.  This lecture will review the evidence supporting the efficacy and the risks of antidepressant and other psychotropic medications in older adults. It will address some of the major issues that impede pharmacotherapy in older adults.  Based on the substantial knowledge accumulated during the last three decades, this lecture will present a practical approach to overcome these clinical problems and maximize the effectiveness of pharmacotherapy when treating older patient with depressive and anxiety disorders.

Target Audience

This activity is intended for physicians, nurses, psychologists, social workers, counselors and other mental health professionals. 

Learning Objectives

At the conclusion of this activity, attendees will be able to:

  1. Assess the evidence supporting the efficacy of psychotropic medications in the treatment of late-life depression
  2. Evaluate the risks of psychotropic medications used in the treatment of late-life depression
  3. Discuss strategies to address treatment-resistant late-life depression (i.e., depression that does not respond to an adequate antidepressant trial).
Course summary
Available credit: 
  • 1.00 ACEP NBCC clock hours
  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 Category II credits for Social Workers
  • 1.00 Psychologists
  • 1.00 MNA Contact Hours for Nurses
  • 1.00 Participation
Course opens: 
12/21/2023
Course expires: 
12/18/2025

Sheppard Pratt’s Professional Education Program is pleased to provide Wednesdays at Sheppard Pratt free of charge as a public service to the mental health community.  Your tax-deductible donations will help maintain the outstanding quality of this service. 

Sheppard Pratt is dedicated to improving quality of life through mental health, special education, and addiction services for children, adolescents, adults and older adults.  Our patient-centered treatment approach, combined with our legacy of clinical excellence, sets us apart from other health systems on both a local and national level.  We have been ranked among the nation’s top psychiatric hospitals for 24 consecutive years by U. S. News & World Report.  Founded in 1853 by philanthropist Moses Sheppard, Sheppard Pratt Health System still abides by its Quaker traditions and values.

Sheppard Pratt regularly hosts renowned speakers from across the country at our headquarters in Towson. We provide educational opportunities on subjects including psychiatric disorders, issues of behavioral health, systems-based change, mental and somatic co-morbidities, psychiatric effects on health and health outcomes, advances in neurobiology, and clinical developments in concepts underlying drug treatment of psychiatric disorders. We are accredited by the Accreditation Council of Continuing Medical Education, the Maryland Nurses’ Association, the Maryland Board of Psychology, the Maryland Board of Social Work, and the National Board of Certified Counselors.

Please send your contributions to:

Sheppard Pratt Professional Education Program
Grand Rounds Fund
6501 North Charles Street, Baltimore, Maryland 21204

Professional Education Program: 410.938.4593
Conference Center at Sheppard Pratt: 410.938.3900

This activity was provided by a grant from the Substance Abuse and Mental Health Services Administration.

About the speaker

Dr. Benoit H. Mulsant, MD, MS, FRCPC, is a Professor and the Labatt Family Chair of the Department of Psychiatry at the Temerty Faculty of Medicine of the University of Toronto, where he also holds the Labatt Family Chair in Biology of Depression in Late-Life Adults. He is an Adjunct Professor of Psychiatry at the University of Pittsburgh, and a Senior Scientist at the Centre for Addiction and Mental Health (CAMH), Toronto.

Dr. Mulsant earned his MD from the Laval University, Quebec; he completed his internship in internal medicine and neurology at McGill University, and his residency in psychiatry at the University of Pittsburgh. He is a Fellow of the Royal College of Physicians and Surgeons of Canada; a Diplomate in Psychiatry, American Board of Psychiatry and Neurology; and a Distinguished Fellow of the American Psychiatric Association and of American Association for Geriatric Psychiatry. He has been listed in Best Doctors in America and Best Doctors in Canada.

Over the past 30 years, Dr. Mulsant has been an investigator on grants with funding totaling more than $174M in direct costs (including $73M as principal investigator or team leader, and $32M as a co-principal investigator). He has authored and co-authored more than 600 peer-reviewed articles (and 65 book chapters and invited publications). His publications (including some in the New England Journal of Medicine, Lancet, and JAMA) have resulted in more than 44,000 citations and an h-index of 102. As an educator, he has successfully mentored several generations of academic psychiatrists.

Disclosure Statements

Sheppard Pratt holds the standard that its continuing medical education programs should be free of commercial bias and conflict of interest. In accord with Sheppard Pratt's Disclosure Policy, as well as standards of the Accreditation Council for Continuing Medical Education (ACCME) and the American Medical Association (AMA), all planners, reviewers, speakers and persons in control of content have been asked to disclose any relationship he /she has with any entity producing, marketing, selling, re-selling, or distributing health care goods or services consumed by, or used on, patients, during the past 24 months. All planners, reviewers and speakers have also been asked to disclose any payments accepted for this lecture from any entity besides Sheppard Pratt, and if there will be discussion of any products, services or off-label uses of product(s) during this presentation.

Benoit H. Mulsant, MD, MS, FRCPC, reports that he has no relationships with any entity producing, marketing, selling, re-selling, or distributing health care goods or services consumed by, or used on, patients, during the past 24 months. He will be discussing antidepressants and psychotropic medications in their generic form in this presentation. 

Event Planners/Reviewers Disclosures: The following event planners and/or reviewers are reported as having no financial interest, arrangement or affiliation with any entity producing, marketing, selling, re-selling, or distributing health care goods or services consumed by, or used on, patients, during the past 24 months: Todd Peters, MD, Deepak Prabhakar, MD, Elizabeth Ryznar, MD, MSc, Louis Marino, MD, Ehsan Syed, MD, Devi Bhuyan, PhD, Faith Dickerson, PhD, Carrie Etheridge, LCSW-C, Tom Flis, LCPC, Stacey Garnett, RN, MSN, Octavia Coit, MN, Heather Billings, RN, Lisa Illum, MLIS, MEd, and Jennifer Tornabene.

Physician Statement: Sheppard Pratt is accredited by The Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.  Sheppard Pratt takes responsibility for the content, quality, and scientific integrity of this CME activity.  Sheppard Pratt designates this enduring activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurse Statement: Sheppard Pratt is approved as a provider of nursing continuing professional development by the Maryland Nurses Association, an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation. Sheppard Pratt takes responsibility for the content, quality, and scientific integrity of this CME activity. This activity provides 1.0 contact hours for nurses.

Psychologist Statement: Sheppard Pratt is authorized by the State Board of Examiners of Psychologists as a sponsor of continuing education. Sheppard Pratt takes responsibility for the content, quality, and scientific integrity of this CE activity.  Sheppard Pratt designates this educational activity for a maximum of 1.0 contact hours for Psychologists.

Social Worker Statement: Sheppard Pratt is authorized by the Board of Social Work Examiners of Maryland to offer continuing education for Social Workers.  Sheppard Pratt takes responsibility for the content, quality, and scientific integrity of this CE activity. This activity is approved for 1.0 contact hours in Category II credits for Social Workers.

Counselor Statement:  Sheppard Pratt has been approved by NBCC as an Approved Continuing Education Provider, ACEP No. 5098.  Programs that do not qualify for NBCC credit are clearly identified.  Sheppard Pratt is solely responsible for all aspects of the program.  This activity is available for 1.0 NBCC clock hours.

Available Credit

  • 1.00 ACEP NBCC clock hours
  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 Category II credits for Social Workers
  • 1.00 Psychologists
  • 1.00 MNA Contact Hours for Nurses
  • 1.00 Participation
Please login or register to take this course.

ON DEMAND WEBINAR: FOR BEST RESULTS WATCH USING GOOGLE CHROME

Grand Rounds: Improving the Outcomes of Antidepressant Pharmacotherapy for Older Adults

Benoit H. Mulsant, MD, MS, FRCPC, DLFAPA

Professor, Labatt Family Chair, Department of Psychiatry

Labatt Family Chair in Biology of Depression in Late-Life Adults

Temerty Faculty of Medicine, University of Toronto

Adjunct Professor of Psychiatry, University of Pittsburg

Senior Scientist, Centre for Addiction and Mental Health (CAMH)

Toronto, Canada

Originally reviewed May 3, 2023.
Originally broadcast live May 3, 2023, from 12:00- 1:00 PM ET
Enduring Activity Credit Expiration Date: December 18, 2025.

Activity Time: One-hour webinar lecture with a 15-minute evaluation process. Total Time: 1:15.

TO EARN CONTINUING EDUCATION CREDIT FOR YOUR ATTENDANCE
On the OVERVIEW or REGISTER/TAKE COURSE tab, select the GREEN RECTANGLE, TAKE COURSE to begin.
Complete the Pretest and select NEXT in the bottom right corner of the screen. Use the NEXT button for best results.
The PowerPoint handout will be available for download.
After downloading the handout, select NEXT to begin and watch the video. 
You may need to select play for the video to begin.
After the video follow the prompts to complete the posttest, evaluation and attestation of credit. 
Once you have completed all the components of the Course Progress bar, the certificate will be immediately downloadable.

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Optimal System Configuration

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Macintosh: Mac OS X 10.3 or higher with latest updates installed; 1.83MHz Intel Core Duo or faster; RAM: 128MB or more; Video Card: at least 64MB of video memory; Sound Card: at least 16-bit

Hardware/Software Specifications

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