There are over four hundred approaches to psychotherapy, most of which branch from the primary streams of knowledge including clinical experience, empirical evidence, theoretical systems, and evidence from related disciplines. What is missing is an organized framework to guide and optimize treatment. The basic building blocks of psychotherapeutics that are fundamental to most approaches are well-documented. Strategic Psychotherapeutics uses these building blocks to inform evidence-based practices, combining the best empirical evidence and clinical expertise, with patient preferences and values. In this presentation, participants will be introduced to the system, which delineates the domains of knowledge that constitute the basic building blocks of psychotherapy. The therapeutic scope and impact of clinicians are enhanced when psychotherapists are grounded in these fundamental knowledge domains and understand how they can be blended. As clinicians gain an understanding of how these basics relate to approaches and technical interventions, more complex therapeutic activities such as assessment, treatment planning, clinical decision making, and alliance maintenance can be appreciated. In this symposium, participants will learn the 11 basic building blocks of psychotherapeutics that can be used to select the approaches and technical interventions best suited to each patient. The goal of this webinar is to enhance clinical expertise by providing the basic, intermediate, and advanced knowledge domains universal to all psychotherapeutics.